Ecosystem
March 12, 2026
StartMidwest

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Eight major Midwestern research universities have opened a shared Bay Area outpost aimed at helping university-affiliated startups and research teams tap Silicon Valley investors, talent and networks. Third Coast Foundry is a two-year pilot, housed in a 3,500-square-foot ground-floor workspace at 625 Second Street in San Francisco’s South Park neighborhood. The space is intended as a short-term base for university founders, researchers and alumni visiting the Bay Area for meetings, events and investor interactions.
The consortium includes Carnegie Mellon, Northwestern, Ohio State, Purdue, University of Chicago, University of Illinois Urbana–Champaign, University of Wisconsin–Madison, and Washington University in St. Louis. Collectively, they said they account for nearly $10 billion in annual research spending and educate more than 300,000 students. Operated by the University of Chicago’s Polsky Center for Entrepreneurship and Innovation, the announcement says that the Foundry will host demo days, workshops, receptions and seminars to help raise the visibility of university startups and create cross‑institutional collaboration opportunities. Sponsorship comes from G2C Venture Partners and the Wisconsin Investment Management Company (WISIMCO).
The Bay area remains both major sources of venture capital and technology talent, and this appears to be increasing as AI investment leads to record setting capital flows. Consortium leaders say a visible presence in the region can shorten the distance between Midwestern innovations and Bay Area investors, facilitate partnerships with companies and accelerators, and help alumni networks engage with founders. The South Park location sits near what organizers describe as an "emerging AI corridor" and established venture capital firms. "This is a significant moment for the Midwest's innovation ecosystem," said Samir Mayekar, managing director of the Polsky Center, in the statement. “By establishing a visible footprint in the Bay Area, we're creating new opportunities for our founders to access capital, talent, and strategic partners, he added.
The collaboration is one of the more notable examples of multiple public and private research universities combining resources to increase their collective access to coastal venture ecosystems.
San Francisco officials welcomed the project as evidence of renewed interest in the city’s commercial core. “We are accelerating our city's recovery,” San Francisco Mayor Daniel Lurie said in a statement from the university consortium, adding "I look forward to welcoming students and leaders from the Midwest and partnering with these universities to open our doors to the next generation of innovators.”
While details on when the Foundry will open have not been shared, but the model will no doubt be closely followed by Midwest universities and investors to see whether a pooled outpost can measurably improve outcomes for participating institutions compared with current efforts.
“This is our minimum viable product,” Samir Mayekar told the San Francisco Chronicle. If it’s successful, and we find our product market fit with this space, then we would absolutely be open to expanding.”