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Indiana Startups: Funding, Investors & Startup News

Indiana startup news and fundraising coverage — from life sciences and agtech innovation to Indianapolis founders building across the Hoosier State's growing ecosystem.

Indiana Startups: Funding, Investors & Startup News

(Almost) Nobody Is Going to Tell You No: How to Translate a VC Pass

(Almost) Nobody Is Going to Tell You No: How to Translate a VC Pass

Andressen Horowitz 1 billion hardware fund is the Midwest as equity partner or tenant

Andressen Horowitz’s $1.1 billion hardware fund: is the Midwest equity partner, or tenant?

Midwest Startup Funding for the week ending September 4 2026

Midwest Startup Funding for the week ending September 4, 2026

Building the plane while it is taking off

Before You Fundraise, Make Sure Your Company Is Real

Midwest Startup Funding for the week ending August 28, 2026

Man in mid air with basketball for Vote in the 2026 Startup Benchmarks Survey

Vote in the 2026 Startup Benchmarks Survey

The Midwest College Rankings 2026

Midwest Startup Funding to August 21 2026

Midwest Startup Funding for the week ending August 21, 2026

A Rocket for the Inc 5000 fastest growing companies

26 Midwest Companies in Top 250 of the Inc. 5000 Fastest Growing 2026

The Secret VC: Midwest Corporate Venture Is Just Private Equity in a Trench Coat

The Secret VC: Midwest Corporate Venture Is Just Private Equity in a Trench Coat

Midwest Startup Funding for the week ending August 14 2026

Midwest Startup Funding for the week ending August 14, 2026

How Midwest builders manage pressure by Aria Spears of Michigan Founders Fund

The Weight Founders Carry: How Midwest Builders Manage Pressure

Pigs might fly but the dollars in Midwest startup funding were strong

Midwest Startup Funding for the week ending August 7, 2026

Corporate Venture Is the Midwest's Home-Field Advantage - Don't Let It Go Dormant

The Secret Founder: Belief isn't the bottleneck, execution is.

The Secret Founder: Belief isn't the bottleneck, execution is.

Indiana’s Canary in the Coal Mine Moment

Indiana’s Canary in the Coal Mine Moment

Piggy on a bath - Midwest Startup funding for week ending July 31 2026

Midwest Startup Funding for the week ending July 31 2026

The infrastructure advantage by Ruby Miller build the shovel not just the goldmine

The infrastructure advantage: build the shovel, not just the goldmine

Midwest Startup Funding for the week ending July 24 2025

Midwest Startup Funding for the week ending July 24 2025

German American Chamber of Commerce visits the Midwest from North Rhine Westphalia Midwest

Is this German region a mirror image of the Midwest?

StartMidwest Startup Funding Q2 2026

Midwest Startup Funding Q2 2026: $1.27 billion across 114 deals

StartMidwest Indiana Funding Q2 2026

Indiana startup funding fell in Q2 2026

StartMidwest Launch Fishers Raise Right Event asked Founders and funders what would help most

Who Are We Actually Building Startup Ecosystems For?

StartMidwest the Midwest Dairy Accelerator in Chicago has chosen six startups for latest cohort

Midwest Dairy Accelerator presents six startups for 2026 cohort

StartMidwest Elanco Ventures Launches in Indiana

Elanco commits $25M to launch animal health venture fund in Indianapolis

StartMidwest Automate Chicago 2026 Humanoid Robot forum

As GM swaps workers for robots in Detroit, Chicago's Automate show previews what's next

The Secret VC: Everyone wants to ‘invest’, no one wants to lead.

StartMidwest - states across the Midwest are considering what to do about data centers

Midwest states courted data centers for years. Now some are asking who pays.

Win the People, Win the Ecosystem

StartMidwest Mollie Kuramoto High Alpha dangers of a broad ICP for early stage startups

Why Midwest Founders Cannot Afford Broad ICPs

StartMidwest Global Tech Ecosystem Index 2026 Lincoln Nebraska

Where Midwest startup hubs rank in Dealroom's 2026 Global Tech Ecosystem Index

The SBA's Patriot Pitch Competition opens applications through June 10, offering a $1M prize pool funded by Clover for SBA-backed small businesses.

SBA $1M Patriot Pitch Competition for 250th anniversary celebrations

Indiana is quietly turning its overlooked waterway borders into ports, container terminals, and trade routes — reshaping what the Crossroads of America moves.

Indiana's Quiet Bet on Ports: Geography Decides and Movement Follows

The Secret Founder why does Midwest fundraising feel like applying for a job

The Secret Founder: Why does Midwest fundraising feel like applying for a job?

Front page of the 2026 State of Talent Access & Hiring Report, a Midwest startup hiring survey by StartMidwest, Digital Reference, and Purpose Jobs.

The State of Talent Access & Hiring Report 2026: What the data tells us.

Red Bull Basement World Final decided after Detroit pitch event

Intalus raises $11M seed, building production hub at Purdue

Indiana Governor Mike Braun announcing the IN AI artificial intelligence initiative for businesses across the state.

Indiana launches IN AI, a statewide initiative to drive employer AI adoption

StartMidwest Secret VC Funds are the entry fee of venture capital

The Secret VC: Funds are the entry fee of Venture Capital. The Real Value is Reputation.

High Alpha at Mira Awards 2026 in Indiana

Defense firm V2X and analytics startup Ekkobar win in Indiana’s 2026 Mira Awards

The Operator Gap: What Midwest Startups Are Missing, and What We Can Do About It

StartMidwest - Fundraising Q1 2026

Midwest startup funding Q1 2026: a record US quarter, but Midwest share shrinks

Iron Nation Indiana - StartMidwest

Indiana commits $15M to fund for US expansion of Israeli startups

StartMidwest - VC Advice whether to raise funds or not - Allie Singer

A Midwest VC’s Guide: To raise or not, tis the question

Most University Innovations Aren’t Meant to Be Startups

The 2026 ‘State of Midwest Innovation Ecosystem’ report with Dealroom

StartMidwest - Sebastian Penix - Where is the Innovation Capital

Are We Evaluating Our Ecosystems? Or Just Counting Money?

Purdue Innovates Accelerator

Purdue Innovates launches second accelerator cohort

Corn Rocket - StartMidwest - Inc Fastest Growing Companies Midwest

What Inc.’s fastest-growing Midwest companies list says about growth

StartMidwest - High Alpha - Midwest Founders Take Longer to Raise

Midwest Founders Raise Just as Well — But It Costs More to Get There

StartMidwest - MidwestHouse Pitch Competition

The invisible work powering SXSW: A first-timer’s perspective

StartMidwest - Moneyball in Minnesota by Ellie Piggott of Traction capital

Is Minnesota Primed for Moneyball Investing?

StartMidwest - SecretVC - Stop Celebrating Mediocrity

The Secret VC: Midwest Investors, stop celebrating mediocrity

Founder Stories: Eric Tobias of Opendate

StartMidwest ‘Significant moment’ for Midwest Innovation Ecosystem as Research Universities Open SF Outpost. Third Coast Foundry

‘Significant moment’ for Midwest Innovation Ecosystem as Research Universities Open SF Outpost.

StartMidwest Do Midwest Ecosystems have an Identity Problem?

Do Midwest Ecosystems have an Identity Problem?

StartMidwest - Straylight Capital - Michelle Erickson - the case for tech enabled services

Human-Powered Trust is the Real Moat: A Case for Tech-Enabled Services

StartMidwest Founder Stories: Justin Turk of ConStrat AI

Founder Stories: Justin Turk of ConStrat AI

StartMidwest author Terry Howerton of TechNexus in Chicago suggests Where the Midwest Should Replicate Silicon Valley

Where the Midwest Should Replicate Silicon Valley

Midwest Moxie: Using sound waves to evaporate tumors - Histosonics

Where Is the Innovation Capital? Midwest Investors Must Catch Up to Their Founders

John Deere announces new cohort of 2026 startup collaborators

The Secret VC The Secret VC: Exit Math Is Destiny - Midwest Funds and Mega Funds are playing different games

The Secret VC: Exit Math Is Destiny - Midwest Funds and Mega Funds are playing different games

Future in the Making: How AI is changing Manufacturing

Why More Midwest SaaS Companies Should Embrace Design Earlier

StartMidwest author Sebastian Penix talks about The Capital Delusion: Why Founders at Every Level Get Funding Wrong

The Capital Delusion: Why Founders at Every Level Get Funding Wrong

Indiana launches $21M life sciences venture fund

StartMidwest author Caroline Wolanin of Straylight Capital asks Should Founders Talk to Junior VCs? The Advice Is Right — and Also Wrong

Should Founders Talk to Junior VCs? The Advice Is Right — and Also Wrong

StartMidwest asks if The Midwest: the new Data-Center Heartland of America?

The Midwest: the new Data-Center Heartland of America?

A New Model in Indiana for Building Rural Health Startups

StartMidwest CES 2026: the future of tech is now physical, industrial, and operational

CES 2026: the future of tech is now physical, industrial, and operational

StartMidwest The Secret VC: Stop Asking "Who Else Is In?”

The Secret VC: Stop Asking "Who Else Is In?”

The Boomerang VC: Ilana Habib on Midwest Grit, Patient Capital, and Building Bigger in Ohio

StartMidwest Midwest funding for Q4 2025

Midwest funding for Q4 2025

StartMidwest The Secret Founder: Hey Midwest VCs, please stop cosplaying Silicon Valley

The Secret Founder: Hey Midwest VCs, please stop cosplaying Silicon Valley

Indiana's 2026 Focus is about Taking Over, Not Starting Over

Midwest Startup investment was poor in 2025. Where to in 2026?

StartMidwest Indiana Startup News 2025: Year in Review

Indiana Startup News 2025: Year in Review

StartMidwest 2025 Midwest startup funding: Year in Review.

2025 Midwest startup funding: Year in Review.

StartMidwest Midwest Startup Founder Stories: Year in Review 2025

Midwest Startup Founder Stories: Year in Review 2025

StartMidwest The Cap Table for Founders: Guide to Equity, Control & Capital

The Cap Table for Founders: Guide to Equity, Control & Capital

StartMidwest How should leaders manage an accusation of inappropriate behavior?

How should leaders manage an accusation of inappropriate behavior?

Indiana’s OYE Therapeutics raises $5.475 million Series A

StartMidwest author Mollie Kuramoto says Midwest Nice Isn’t a Bad Thing. But It’s Also Not Enough.

Midwest Nice Isn’t a Bad Thing. But It’s Also Not Enough.

Lilly and Indiana University Expand Clinical Trial Access and Innovation

StartMidwest Founder Stories: Charlie & Madeline of Intero Biosystems

Founder Stories: Charlie & Madeline of Intero Biosystems

StartMidwest Nebraska startup CompanyCam becomes first unicorn in that state after $415m round

Nebraska startup CompanyCam becomes first unicorn in that state after $415m round

StartMidwest Applications Open for 2026 US Women in Tech Accelerator

Applications Open for 2026 US Women in Tech Accelerator

Founder Stories: Scott & Bryce of Midwest vs… the Rest?

StartMidwest author Madelyn Rutter of Technexus in Chicago explains that to Raise From a Midwest CVC provides a True Strategic Partner

Why Raise From a Midwest CVC? For a True Strategic Partner

StartMidwest The Secret VC: Why Hustle Culture Is Toxic AF

The Secret VC: Why Hustle Culture Is Toxic AF

Indianapolis’ Athian Announces $18M in Farmer Payments and closes $4M Series A

Indiana-based Sortera Technologies raises $45 Million in Funding for Mixed Aluminum

StartMidwest Future in the Making Podcast with Chris Nolte Hidden Factories

Future in the Making: Hidden Factories

New additions to Indiana’s OneHealth Innovation District: Human, Animal, and Plant Health

StartMidwest author Sebastian Penix asks WTF is an Ecosystem anyways?

WTF is an Ecosystem anyways?

Purdue and Google Expand AI Research and Education Initiatives

StartMidwest A New Transatlantic Bridge Launches During Global Entrepreneurship Week

A New Transatlantic Bridge Launches During Global Entrepreneurship Week

StartMidwest 2025 SaaS Benchmarks: Where the Midwest Is Winning (and Where It Lags)

2025 SaaS Benchmarks: Where the Midwest Is Winning (and Where It Lags)

StartMidwest The Secret Founder: How Ecosystems Fail (and what it means for all of us)

The Secret Founder: How Ecosystems Fail (and what it means for all of us)